Auto-antibodies in Acquired Haemolytic Anaemia
نویسندگان
چکیده
منابع مشابه
Auto-antibodies in acquired haemolytic anaemia.
It is now widely recognized that cases of haemolytic anaemia of spontaneous or endogenous origin may be divided into two broad groups: those determined by a genetical cause resulting in the production of defective red cells, and those not so determined. Among the latter group of acquired haemolytic anaemias are cases in which there is evidence for the presence of antibodies active against the p...
متن کاملSpecificity of auto-antibodies in acquired haemolytic anaemia.
Until recently it has been assumed that the autoantibodies found in acquired haemolytic anaemia are non-specific; that is to say they react with all types of human red cells and are unrelated to any known blood group antibodies. However, Weiner, Battey, Cleghorn, Marson, and Meynell (1953) have described a patient in whom the auto-antibody had the specificity anti-e, the patient's red cells hav...
متن کاملCross-matching Technique in Acquired Haemolytic Anaemia
W. WEINER (Birmingham) said that, until a short time ago, it was thought that one of the differences between acquired and inherited haemolytic anaemias was the fact that in the former the life span of transfused blood was shortened as against the normal survival time in the latter. It could, however, be shown that the short survival time was due to the fact that incompatible blood had been tran...
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BACKGROUND In autoimmune haemolytic anaemia (AIHA), autoreactive antibodies directed against red blood cells are up-regulated, leading to erythrocyte death. Mycoplasma suis infections in pigs induce AIHA of both the warm and cold types. The aim of this study was to identify the target autoantigens of warm autoreactive IgG antibodies. Sera from experimentally M. suis-infected pigs were screened ...
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Polyagglutination is an abnormality of red cells so that they are aggulutinated by most normal sera, except that from very young infants. Polyagglutination occurs in red cells which have been infected in vitro. Rarely it occurs in vivo, when it has usually been associated with severe bacterial infection. There are very few reported cases where polyagglutinability has led to increased red cell d...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1951
ISSN: 0021-9746
DOI: 10.1136/jcp.4.3.253